The ephedrine alkaloids present in the plant contain sympathomimetic compounds and are a source of ephedrine and pseudophedrine, which are used in many decongestants and cold medicines. Ephedra is derived from a shrub that is native to China ( Ephedra sinica) and has been used for more than 5000 years as a natural treatment for asthma and other conditions. What is Ephedra?Įphedra (also known as Ma Huang) is a plant and is the source for most ephedrine products. market in 2004 because the risk of its use was deemed greater than its benefits for weight loss. Food and Drug Administration (FDA) removed ephedra products from the U.S. Because of several safety concerns-hypertension, arrhythmias, heart attack, stroke, and even death-the U.S. The effect of glucomannan on body weight in overweight or obese children and adults: A systematic review of randomized controlled trials.Ephedra Fat Burners (Ephedra-Containing Supplements)Įphedra, also known as ma huang, is probably one of the most widely recognized nutritional supplements used for weight loss. Bleeding risks with aspirin use for primary prevention in adults: Systematic review for the U.S. Psychiatric effects of Ephedra use: An analysis of Food and Drug Administration reports of adverse events. Legal requirements for the sale and purchase of drug products containing pseudoephedrine, ephedrine, and phenylpropanolamine.Multi-ingredient, caffeine-containing dietary supplements: History, safety, and efficacy. Guidance for industry: Final rule declaring dietary supplements containing ephedrine alkaloids adulterated because they present an unreasonable risk small entity compliance guide.Mechanism, efficacy, and safety of an ephedrine, caffeine, and aspirin combination in the treatment of obesity. Ephedra and ephedrine alkaloids for weight loss and athletic performance.Cardiovascular toxicities of performance-enhancing substances in sports. You can learn more about how we ensure our content is accurate and current by reading our editorial policy. Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. Long-term use of aspirin, even in small doses, has been associated with an increased risk of bleeding in the gastrointestinal tract. In other words, its helps maintain the stimulation effects that the caffeine and ephedrine help provide. When taken as part of an ECA stack, aspirin prevents norepinephrine levels from decreasing. Caffeine consumption can increase feelings of alertness, effectively reducing fatigue.īut when taken in large doses, caffeine can also cause:Īspirin is a pain reliever. It’s commonly found in coffee, tea, and soft drinks. CaffeineĬaffeine is also a stimulant of both the CNS and the cardiovascular system. This makes it an important part of the fight-or-flight response during times of high stress.Įphedra also raises heart rate and can also cause constriction of blood vessels, leading to high blood pressure. Norepinephrine is used to get the body ready for action and activity.
This extract stimulates the central nervous system (CNS) through release of a compound called norepinephrine. It’s been used in traditional Chinese medicine for centuries and is also referred to as “ma huang.” Ephedrine is derived from the Ephedra plant.
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